The causes of venous disease are not clearly identified yet. However, we know that heredity factors play an important role : if both parents have the disease, there is a 90% chance of developing a venous disorder.
In addition to heredity, there are other factors to consider such as :
- age
- gender
- excessive weight
- pregnancy
- hormonal treatments
- professions requiring prolonged standing or sitting
The most important condition leading to chronic venous insufficiency is thrombosis as valves are destroyed when the vessel is cleared from the clots.